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研究人员一种更容易和更安全合成药物的方法_我的网站

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一 |     New Delhi, Oct 12 (UNI) Indian Army has launched a drive to introduce Electric Vehicles (EVs) into select units that will significantly reduce the carbon emissions and dependency on fossil fuels.

According to the plans, a detailed roadmap has been prepared to ensure that 25 per cent light vehicles, 38 per cent buses and 48 per cent motor cycles of the select Army units are changed to Electric Vehicles soon with adequate charging infrastructure, officials said.

In April 2022, the Indian Army had organised a demonstration of available EVs to Defence Minister Rajnath Singh where Electric Vehicle manufactures from Tata Motors, Perfect Metal Industries (PMI) and Revolt Motors showcased their EVs and briefed about the enhancement in technology and range of operation achieved during past few years.

The drive to introduce Electric Vehicles in the Indian Army gained further momentum after the demonstration.

Various factors unique to Indian Army’s employability, remote locations of employment and operational commitments were considered to arrive at a definite time bound roadmap.

Introduction of Electric Vehicles is considered as one of the effective steps to reduce Carbon Emission and reduce dependency on fossil fuel.

"India has emerged as one of the leaders to exceed global targets of reducing greenhouse gas emissions by 2030 and 2070. Many projects are being implemented to reduce the carbon emissions and dependency on fossil fuels," officials said.

In order to support a viable Electric Vehicles ecosystem in the Army, support infrastructure is also being established like EV charging points in the parking lots of offices/ residential complexes for on board charging.

These EV charging stations will have at least one fast charger and two to three slow chargers.

Besides, electric circuit cables, Transformers with adequate load bearing capability based on anticipated number of EVs per station are being ensured.

Solar Panel Driven charging stations are also planned in a phased manner to bring carbon footprint of these EVs to near zero.

Keeping in view the necessity and employability of EVs over various terrains, the Army will equip few units located in Peace Stations with EVs sequentially.

The Indian Army is also procuring EVs through the Capital Route.

As per plans, the existing deficiency of Buses will be fulfilled by procuring Electric Buses for select Peace Establishments for initial exploitation.

An Open Tender Enquiry for procurement of 60 Buses (Electric) along with 24 Fast Chargers will soon be floated, officials said.

The drive for Electric Vehicles will establish the right momentum for setting up the ecosystem for further induction of EVs in the Armed Forces, officials added.

Apart from these, Army has already started using EVs as part of Civil Hired Transport (CHT). Stations like Delhi Cantonment have already established charging stations to support EVs being hired or inducted subsequently.

At Delhi Cantt, a number of charging stations is also open to civilians.



UNI ASU SY ING。    该研究的共同作者、俄亥俄州立大学化学和生物化学教授David Nagib说:"碳化物具有难以置信的能量。这一点的价值在于它们可以做你无法用其他方式做的化学实验。"Nagib实验室的成员擅长利用具有巨大化学能量的试剂,并为开发大量的新物质和工艺做出了贡献。在这项研究中,研究人员用廉价的、地球上丰富的金属如铁、铜和钴创造了催化剂,并将它们结合起来,以促进他们驾驭碳烯的新方法。他们成功地引导活性碳烯的力量,以更大的规模和比标准方法更快的速度制造出有价值的分子。Nagib将这一发展比作工程师发现如何使用钢铁而不是砖块和砂浆来建造摩天大楼的时刻。例如,化学家们一直难以创造的一个分子特征是环丙烷,这是一个由扭曲的化学键组成的小而紧的环状结构,在一些药物中特别有用。最近,环丙烷被用作名为Paxlovid的口服抗病毒药的一种关键成分,该药片用于治疗COVID-19,通过阻止病毒的复制而不是直接杀死它来降低疾病的严重程度。

二 | 制造这种药物所需的环丙烷一直难以大量制造,但Nagib说,他相信他的实验室的新方法可以应用于更快和更大规模地制造这种药物。他说:"我们的新方法将使人们能够更好地获得数十种环丙烷,以纳入各种治疗疾病的药物中。"虽然该团队的研究确实在制药领域之外有潜在的应用,比如农用化学品,但Nagib说他最热衷的是他们的工具如何能加快发现新的、有针对性的药物。他说:"从技术上讲,你可以将我们的方法应用于任何产品。但是在我们的实验室里,我们对获得新型的更有效的药物更感兴趣。"Nagib预测,使用他的团队开发的工艺,目前需要10或12个步骤才能制成的化学试剂(通过爆炸性的中间体)可以在4或5个步骤内完成,将其制造的时间减少了近75%,他希望这项研究能够帮助其他化学家完成他们的工作。Nagib说:"世界上有很多伟大的科学家在做这种化学研究,使用我们的工具,他们可能会有一个更安全的实验室。

三 | 我们所做的科学研究最令人满意的回报是当其他人使用我们的化学方法时,会使重要的分子变得更好。"了解更多:https://www.science.org/doi/10.1126/science.abo6443

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Published on:00:38:18